Kai Zhao
Assistant Member
Education
Ph.D., Bioengineering; University of Pennsylvania
Research Summary
My research interests include: 1) computational simulation of airflow and chemical odorant deposition in the human nasal cavity; 2) numerical modeling of peri-receptor chemical transport events, and exploring the possible influence of physio-chemical and local physiological variables (e.g., odorant mucosal solubility and diffusivity, nasal blood flow, etc.) on human olfactory and trigeminal responses; and 3) clinical evaluation of nasal mechanical obstruction caused by various nasal diseases and their treatment.
Recent Publications
Jiang, J. B. and Zhao, K. (2010) “Airflow and nanoparticle deposition in rat nose under various breathing and sniffing conditions — A computational evaluation of the unsteady and turbulent effect.” Journal of Aerosol Science. 41, 1030–1043
Wise, P. M.; Zhao, K. and Wysocki, C. J. (2009) “Dynamics of nasal chemesthesis.” Annals of the New York Academy of Science. 1170, 206-14.
Yang, G. C.; Scherer, P. W.; Zhao, K. and Mozell, M. M. (2007) “Numerical modeling of odorant uptake in the rat nasal cavity.” Chemical Senses. 32, 273-84.
Zhao, K.and Dalton, P. (2007) “The way the wind blows: implications of modeling nasal airflow.” Current Allergy and Asthma Reports. 7, 117-25.
Zhao, K.; Pribitkin, E. A.; Cowart, B. J.; Rosen, D.; Scherer, P. W. and Dalton, P. (2006) “Numerical modeling of nasal obstruction and endoscopic surgical intervention: outcome to airflow and olfaction.” American Journal of Rhinology. 20, 308-16.
Zhao, K.; Dalton, P.; Yang, G. C. and Scherer, P. W. (2006) “Numerical modeling of turbulent and laminar airflow and odorant transport during sniffing in the human and rat nose.” Chemical Senses. 31, 107-18.
Kurtz, D. B.; Zhao, K.; Hornung, D. E. and Scherer, P. W. (2004) “Experimental and numerical determination of odorant solubility in nasal and olfactory mucosa.” Chemical Senses. 29, 763-773.



