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Chemical irritants, both noxious (e.g., tear gas or hot pepper) and
mild (e.g., menthol or carbonation), act on pain as well as thermal and
tactile receptors. I use fluorescence imaging of intracellular calcium
and nerve recordings to characterize the transduction processes and coding
mechanisms involved in chemical irritation. Knowledge of these mechanisms
has applications ranging from foods and beverages through pharmaceuticals
and personal care products to designing repellents for managing animal
pests.
My Monell Publications |