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To gain a better understanding
of taste transduction, I am isolating and identifying
taste-related genes from taste cDNA libraries. To then
place these discoveries in
a cellular context, we analyze gene expression profiles
of microdissected individual taste cells. One recently
discovered gene codes for the
key enzyme in the conversion of tryptophan to serotonin.
The cellular specificity of the enzyme and the role
of serotonin in taste transduction
are being studied.
My Monell Publications |