My
research mainly focuses on molecular mechanisms underlying taste
perception.
To elucidate the function of genes that are selectively
expressed in taste bud cells, I
use transgenic tools, produce animals with mutated genes
to perturb normal taste bud
cell physiology, and then assay the effect of these mutations
on taste transduction. In
addition, I am also interested in delineating the anatomical
relationships between
taste bud cells and their innervating cranial nerve fibers,
and defining neuronal
pathways from taste buds to the gustatory cortex.
My Monell Publications |