Individual differences abound
in human olfaction. I have been exploring contributions
to this variation, which include genetics, development,
sex, aging, environment and
experience. In my laboratory, animal models of human
specific anosmia (selective olfactory deficits) have
been developed and are being
studied at similar levels of investigation. Individual
sensitivity to intranasal irritants and their interactions
with olfaction also
are being explored to delineate quality coding within
the nasal trigeminal system. In a third area of research,
we are working closely with
chemists in the laboratory of Dr. Preti on programs
that explore issues related to adaptation and cross-adaptation
in studies of structure-activity
relationships, especially as they relate to malodors,
for example, those originating from agricultural endeavors.
We also continue our
long-lasting studies on chemical communication and
have been focusing our efforts on humans.
My Monell Publications |