Typical housing conditions for mice in the MMTPP

Feed: Teklad Rodent Diet 8604 (Harlan, Madison, WI).

Water: Deionized water.

Housing: Individually housed in 26.5 x 17 cm x 12 cm plastic tub cages with stainless steel grid tops (Lab products, Inc no. 10025).

Bedding: Aspen Chips, provided by North Penn Feeds.

Photoperiod: 12 hours on (on at 6 am) 12 hours off.

Temperature: 23 ± 2 C

Relative humidity: Approximately 35% but not monitored.

Health status : Sentinel mice in each vivarium are checked every 3-6 mo for a number of viruses, using a Mouse Assessment Plus test from Charles River Professional Services (included SEND, PVM, MHV, TMEV, REO, MPUL, MPV, EDIM, LCMV, MAV, ECTRO, K, POLY, MYLV, MCMV, HTN, ECUN, and CARB).