Robert F. Margolskee, MD, PhD, is Director of the Monell Chemical Senses Center.
A pioneer in the use of molecular biology to study cellular mechanisms of taste, Dr. Margolskee has been responsible for major advances in the field of taste biology. He joined Monell’s faculty in 2009 and was appointed Associate Director in 2010. In August 2014, he was selected by Monell’s Board to become the Center’s third Director.
Dr. Margolskee’s seminal discovery of gustducin, a signaling protein expressed selectively in taste cells, provided the critical knowledge needed to explain how taste receptors detect sweet, bitter and savory tasting molecules. More recently, his research has focused on the mechanisms and functions of taste receptors located in the gastrointestinal tract and in other organs throughout the body.
Dr. Margolskee received his undergraduate degree from Harvard University and his MD-PhD in Molecular Genetics from Johns Hopkins University, where he studied with the late Nobel laureate Dr. Daniel Nathans. He carried out postdoctoral studies in molecular biology at Stanford University with the Nobel laureate Dr. Paul Berg, then moved to the Roche Institute of Molecular Biology. While on the faculty of the Mount Sinai School of Medicine, he was an Associate Investigator of the Howard Hughes Medical Institute from 1997 to 2005. Dr. Margolskee is an author on over 130 peer-reviewed articles, which have been published in such prestigious journals as Nature, Science, Proceedings of the National Academy of Sciences, and Scientific American.
“Monell is the preeminent center in the world for studying the chemical senses of taste and smell, and it is a privilege to lead the Center’s group of outstanding scientists. This is a wonderful time for biomedical research where stunning discoveries are being made every day, including within the chemical senses at Monell.”
ROBERT F. MARGOLSKEE, MD, PhD