Contact Information

(267) 519-4710

Gary Beauchamp

Director & Member

Education

Ph.D., Biopsychology; The University of Chicago

Research Summary

My research interests include: 1) genetics of taste perception; 2) development of human chemosensory perception and preference; 3) genetics and behavior of individual olfactory identity; and 4) adult human flavor perception.

Keywords

salt, sweet, umami, acceptance, genetics, odortype, MHC, food choice, development, oleocanthal

Recent Publications

Matsumura, K., Opiekun, M., Oka, H., Vachani, A., Albelda, S. M., Yamazaki, K., & Beauchamp, G. K. (2010). Urinary volatile compounds as biomarkers for lung cancer: a proof of principle study using odor signatures in mouse models of lung cancer. PLoS.One., 5, e8819.

Beauchamp, G. K. (2009). Sensory and receptor responses to umami: an overview of pioneering work. American Journal of Clinical Nutrition, 90, 723S-727S.

Bachmanov, A. A., Inoue, M., Ji, H., Murata, Y., Tordoff, M., & Beauchamp, G. K. (2009). Glutamate taste and appetite in laboratory mice: physiologic and genetic analyses. American Journal of Clinical Nutrition, 90, 756S-763S.

Peyrot des Gachons, C., Beauchamp, G. K., & Breslin, P. A. S. (2009). The genetics of bitterness and pungency detection and its impact on phytonutrient evaluation. Annals of the New York Academy of Sciences, 1170, 140-144.

Mennella JA, Forestell CA, Morgan LK, Beauchamp GK. (2009). Early milk feeding influences taste acceptance and liking during infancy. American Journal of Clinical Nutrition, 90, 780S-788S.

Li, X., Glaser, D., Li, W., Johnson, W. E., O’Brien, S. J., Beauchamp, G. K., & Brand, J. G. (2009). Analyses of sweet receptor gene (Tas1r2) and preference for sweet stimuli in species of Carnivora. Journal of Heredity, 100, S90-S100.

Beauchamp, G. & Mennella, J. A. (2009). Early flavor learning and its impact on later feeding behavior. Journal of Pediatric Gastroenterology and Nutrition, 48, S25-S30.

Cicerale, S., Breslin, P. A. S., Beauchamp, G. K., & Keast, R. S. J. (2009, electronic publication). Sensory characterization of the irritant properties of oleocanthal, a natural anti-inflammatory agent in extra virgin olive oils. Chemical Senses. doi:10.1093/chemse/bjp006

Field, K. L., Bachmanov, A. A., Mennella, J. A., Beauchamp, G. K., & Kimball, B. A. (2009). Protein hydrolysates are avoided by herbivores but not by omnivores in two-choice preference tests. PLoS ONE, 4, e4126.

Kwak, J., Curran-Opiekun, M., Matsumura, K., Preti, G., Yamazaki, K., & Beauchamp, G. K. (2009). Major histocompatibility complex-regulated odortypes: Peptide-free urinary volatile signals. Physiology & Behavior, 96, 184-188.

Field, K. L., Kimball, B. A., Mennella, J. A., Beauchamp, G. K., & Bachmanov, A. A. (2008). Avoidance of hydrolyzed casein by mice. Physiology & Behavior, 93, 189-199.

Inoue, M., Glenndinning, J. I., Theodorides, M., Harkness, S., Li, X., Bosak, N. et al. (2008). Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice. Physiological Genomics, 32, 82-94.

Kwak, J., Willse, A., Matsumura, K., Preti, G., Yamazaki, K., & Beauchamp, G. K. (2008, electronic publication). Genetically-based olfactory signatures persist despite dietary variation. PLoS ONE. doi:10.1371/journal.pone.0003591

Mennella, J. A. & Beauchamp, G. K. (2008). Optimizing oral medications for children. Clinical Therapeutics, 30, 2120-2132.

Shigemura, N., Ohkuri, T., Sadamitsu, C., Yasumatsu, K., Yoshida, R., Beauchamp, G. K. et al. (2008). Amiloride-sensitive NaCl taste responses are associated with genetic variation of ENaC -subunit in mice. American Journal of Physiology, 294, R66-R75.

Bachmanov, A. A. & Beauchamp, G. K. (2007). Amino acid and carbohydrate preferences in C57BL/6ByJ and 129P3/J mice. Physiology & Behavior, 93, 37-43.

Bachmanov, A. A. & Beauchamp, G. K. (2007). Taste receptor genes. Annual Review of Nutrition, 27, 389-414.

Yamazaki, K. & Beauchamp, G. K. (2007). Genetic basis for MHC-dependent mate choice. Advances in Genetics, 59, 129-145.

Li, X., Li, W., Wang, H., Bayley, D. L., Cao, J., Reed, D. R. et al. (2006). Cats lack a sweet taste receptor. Journal of Nutrition, 136 (7Suppl), 1932S-1934S.

Manita, S., Bachmanov, A. A., Li, X., Beauchamp, G. K., & Inoue, M. (2006). Is glycine “sweet” to mice? Mouse strain differences in perception of glycine taste. Chemical Senses, 31, 785-793.

Mennella, J. A., Kennedy, J., & Beauchamp, G. K. (2006). The type of formula fed to infants modifies vegetable acceptance. Early Human Development, 82, 263-268.

Restrepo, D., Lin, W., Salcedo, E., Yamazaki, K., & Beauchamp, G. K. (2006). Odortypes and MHC peptides: complimentary chemosignals of MHC haplotype? Trends in Neurosciences 29, 604-609.

Stein, L. J., Cowart, B. J., & Beauchamp, G. K. (2006). Salty taste acceptance by infants and young children is related to birth weight: longitudinal analysis of infants within the normal birth weight range. European Journal of Clinical Nutrition, 60, 272-279.

Willse, A., Kwak, J., Yamazaki, K., Preti, G., Wahl, J. H., & Beauchamp, G. K. (2006). Individual odortypes: Interaction of MHC and background genes. Immunogenetics 58, 967-982.

Beauchamp, G. K., Keast, R. S. J., Morel, D. L. J., Pika, J., Han, Q., Lee, C.-H. et al. (2005). Ibuprofen-like activity in extra-virgin olive oil. Nature, 437, 45-46.

Beauchamp, G. K. & Yamazaki, K. (2005). Individual differences and the chemical senses. Chemical Senses, 30 Suppl 1, i6-i9.

Li, X., Li, W., Wang, H., Cao, J., Maehashi, M., Huang, L. et al. (2005). Pseudogenization of a sweet receptor gene accounts for cats’ indifference toward sugar. PLoS Genetics, 1, e3.

Lu, K., McDaniel, A. H., Tordoff, M. G., Li, X., Beauchamp, G. K., Bachmanov, A. A. et al. (2005). No relationship between sequence variation in protein coding regions of the Tas1r3 gene and saccharin preference in rats. Chemical Senses, 30, 231-240.

Mennella, J. A. & Beauchamp, G. K. (2005). Understanding the origin of flavor preferences. Chemical Senses, 30 Suppl 1, i242-i243.

Smith, A. B., III, Han, Q., Breslin, P. A. S., & Beauchamp, G. K. (2005). Synthesis and assignment of absolute configuration of (-)-oleocanthal: a potent, naturally occurring non-steroidal anti-inflammatory and anti-oxidant agent derived from extra virgin olive oils. Organic Letters, 7, 5075-5078.