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(267) 519-4780
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Paul Breslin


Member, Monell Chemical Senses Center
Professor, Department of Nutritional Sciences, Rutgers University
Adjunct Professor, Department of Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania


Ph.D., Experimental Psychology; University of Pennsylvania

Research Summary

I am interested in human oral perception and its genetic basis. The primary focus of my work is on taste perception with an emphasis on taste discrimination, taste enhancement and suppression, and taste localization. I also study oral irritation/chemesthesis, mouthfeel, and astringency. The interactions among gustation, chemesthesis, and olfaction that comprise flavor are the topic of an ongoing research program that includes fMRI as a tool to understand regional brain involvement. In addition to human research, I conduct parallel genetic studies of the chemical senses in my Fly Lab, which uses Drosophila melanogaster as a model.


taste, psychophysics, behavioral genetics, perceptual genetics, psychogenomics, oral rheometry, functional expression

Recent Publications

Wise, P.M.; Breslin, P.A.S. (2013) Individual Differences in Sour and Salt Sensitivity: Detection and Quality Recognition Thresholds for Citric Acid and Sodium Chloride. Chemical Senses. doi: 10.1093/chemse/bjt003

Peyrot des Gachons, C.P.; Mura, E.; Speziale, C.; Favreau, C.J.; Dubreuil, G.F.; Breslin, P.A.S (2012) Opponency of astringent and fat sensations. Current Biology, 22, R829-830.

Campbell, M.C.; Ranciaro, A.; Froment, A.; Hirbo, J.; Omar, S.; Bodo, J.-M.; Nyambo, T.; Lema, G.; Zinshteyn, D.; Drayna, D.; Breslin, P.A.S.; Tishkoff, S.A. (2012) Evolution of functionally diverse alleles associated with PTC bitter taste sensitivity in Africa. Molecular Biology and Evolution, 29, 1141-1153.

Mandel, A.L.; Breslin, P.A.S. (2012) High endogenous salivary amylase activity is associated with improved glycemic homeostasis following starch ingestion in adults. Journal of Nutrition, 142, 853-858, [Cover Article].

Wise, P.M.; Breslin, P.A.S.; Dalton, P. (2012) Sweet taste and menthol increase cough reflex thresholds. Pulmonary Pharmacology and Therapeutics, 25, 236-241.

Greene, T.A.; Alarcon, S.; Thomas, A.; Berdougo, E.; Doranz, B.J.; Breslin, P.A.S.; Rucker, J. (2011) Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin. PLOS One, 6:e20123.

Wise, P.; Breslin, P.A.S. (2011) Relationships among taste qualities assessed with response-context effects. Chemical Senses, 36, 581-587.

Ozdener, M.H.; Brand, J.G.; Speilman, F.G.,; Lischka, F.W.; Teeter, J.; Breslin, P.A.S.; Rawson, N.E. (2011) Characterization of human fungiform papillae cells in culture. Chemical Senses, 36, 601-612.

Peyrot des Gachons, C.; Uchida, K.; Bryant, B.P.; Shima, A.; Sperry, J.B.; Dankulich-Nagrudny, L.; Tominaga, M.; Smith, A.B. III; Beauchamp, G.K.; Breslin, P.A.S. (2011) Unusual pungency from extra-virgin olive oil is attributable to restricted spatial expression of the receptor of oleocanthal. Journal of Neuroscience, 31, 999-1009.

Peyrot des Gachons, C.; Beauchamp, G.K.; Stern, R.M.; Koch, K.L.; Breslin, P.A.S. (2011) Bitter taste induces nausea. Current Biology, 21, R247-R248.

Feng, P.; Wang, H.; Feldman, R.S.; Pribitkin, E.A.; Breslin, P.A.S. (2010) The T Cells in peripheral taste tissue of healthy human adults: Predominant memory T cells and Th-1 cells. Chemical Senses, 35, 501-509.

Related Links

Director, Monell Science Apprenticeship Program