Contact Information

(267) 519-4677
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Chanyi Lu

Affiliations

Postdoctoral Fellow, Monell Chemical Senses Center

Laboratory of

Dr. Peihua Jiang

Education

Ph.D., Microbiology, Fudan University (Shanghai, China)

Research Summary

Tuft cells are chemosensory cells in the intestinal epithelium which express a number of taste-signaling elements. Despite being discovered decades ago, the function of tuft cells in the small intestine was only recently discovered. Tuft cells mediate host defense against parasitic infection or other pathogens by regulating type 2 immunity. My research interest is clarifying the parasites’ ligands and sensing receptors in tuft cells.

Keywords

Tuft cells, type 2 immunity, parasitic infections

Recent Publications

Srinivasalu N*, Lu C*, Pan M, Reinach PS, Wen Y, Hu Y, Qu J, Zhou X. Novel biomarkers distinguishing active tuberculosis from latent infection identified by gene expression profile of peripheral blood mononuclear cells. Invest Ophthalmol Vis Sci. 2018 Aug 1;59(10):4318-4325. (*equal contribution)

Lu C, Wu J, Wang S, Wang F, Zhang W, Wang H. Novel biomarkers distinguishing active tuberculosis from latent infection identified by gene expression profile of peripheral blood mononuclear cells. PLoS One. 2011, 6(8):e24290.