Contact Information

(267) 519-4915
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Danielle Reed

Affiliations

Member, Monell Chemical Senses Center

Education

Ph.D., Psychology; Yale University

Research Summary

We do studies to understand the exact relationship between genotype and phenotype in both animal models and in human subjects including twins. Phenotypes of interest include taste perception, food preferences and obesity.

Detailed description of research program

Keywords

sweet, genetics, taste, smell, obesity, genomics, genetic mapping

Recent Publications

Reed, D.R.; Xia, M.B. (2015) Recent advances in fatty acid perception and genetics. Advances in Nutrition, 6, 353S-360S.

Mennella, J.A.; Reed, D.R.; Mathew, P.S.; Roberts, K.M.; Mansfield, C.J. (2015) “A spoonful of sugar helps the medicine go down”: bitter masking by sucrose among children and adults. Chemical Senses, 40, 17-25.

Mennella, J.A.; Reed, D.R.; Roberts, K.M.; Mathew, P.S.; Mansfield, C.J. (2014) Age-related differences in bitter taste and efficacy of bitter blockers. PLoS ONE, 9, e103107.

Jiang, P.; Josue-Almqvist, J.; Jin, X.; Li, X.; Brand, J.G.; Margolskee, R.F.; Reed, D.R.; Beauchamp, G.K. (2014) The bamboo-eating giant panda (Ailuropoda melanoleuca) has a sweet tooth: Behavioral and molecular responses to compounds that taste sweet to humans. PLoS ONE, 9, e93043.

Mennella, J.A.; Finkbeiner, S.; Lipchock, S.; Liang-Dar, H.; Reed, D.R. (2014) Preferences for Salty and Sweet Tastes Are Elevated and Related to Each Other during Childhood. PLoS ONE, 9, e92201.

Adappa, N.D.; Zhang, Z.; Palmer, J.N.; Kennedy, D.W.; Doghramji, L.; Lysenko, A.; Reed, D.; Scott, T.; Zhao, N.W.; Owens, D.; Lee, R.J.; Cohen, N.A. (2014) The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring sinus surgery. International Forum of Allergy and Rhinology, 4, 3-7.

Mennella, J.A.; Reed, D.R.; Roberts, K.M.; Mathew, P.S.; Mansfield, C.J. (2014) Age-related differences in bitter taste and efficacy of bitter blockers. PLoS ONE, 9, e103107.

Mennella, J.A.; Roberts, K.; Mathew, P.S.; Reed, D.R. (In Press) Medication use among children: Genetics and Taste. Archives of Diseases of Childhood.

Adappa, N.D.; Howland, T.J.; Palmer, J.N.; Kennedy, D.W.; Doghramji, L.; Lysenko, A.; Reed, D.R.; Lee, R.J.; Cohen, N.A. (2013) Genetics of the taste receptor T2R38 correlates with chronic Rhinosinusitis necessitating surgical intervention. International Forum of Rhinology and Allergy Journal, 3, 184-187.

Bachmanov, A.A.; Bosak, N.P.; Lin, C.; Matsumoto, I.; Ohmoto, M.; Reed, D.R.; Nelson, T.M. (2013) Genetics of taste receptors. Current Pharmaceutical Design, (Electronic citation) PMID: 23886383

Lin, C.; Theodorides, M.L.; McDaniel, A.H.; Tordoff, M.G.; Zhang, Q.; Li, X.; Bosak, N.; Bachmanov, A.A.; Reed, D.R. (2013) QTL analysis of dietary obesity in C57BL/6ByJ X 129P3/J F2 mice: diet- and sex-dependent effects. PloS ONE, 8, e68776.

Lipchock, S.V.; Mennella, J.A.; Spielman, A.I.; Reed, D.R. (2013) Human bitter perception correlates with bitter receptor messenger RNA expression in taste cells. American Journal of Clinical Nutrition, 98, 1136-1143.

Mennella, J.A.; Spector, A.C.; Reed, D.R.; Coldwell, S.E. (2013) The bad taste of medicines: Overview of basic research on bitter taste. Clinical Therapeutics, 35, 1225-1246.

Lab Staff

Cailu Lin Ph.D., Research Associate (with Alexander Bachmanov)
Natalia Bosak Ph.D., Research Associate (with Alexander Bachmanov)
Corrine Mansfield, B.S., Lab Manager
Brad Fesi, B.S., Research Technician
Charles J. Arayata B.S, M.A., Research Technician
Lauren Shaw, University of Pennsylvania, Roy and Diana Vagelos Scholars Program
Jennifer Douglas, B.S., University of Pennsylvania medical student (with Noam Cohen)
Amanda McKnight, M.L.S., Monell Library

Past Reed Lab Members

Kellen Wartnow – University of Pennsylvania undergraduate
Emily Evans – graduate of Washington College
Molly Stein – University of Pennsylvania undergraduate
Wendy Yu, Masters student – currently in Mainland lab
Gabriel Galson, Library – Bibliographic Assistant II, Temple University
Paule V. Joseph, Graduate student – NIH postdoc in Wendy Henderson’s lab
Sarah V. Lipchock – Guston School
Deborah Lee, Research technician – medical school
Michael Marquis, Research technician – Harvard College, PhD in Neuroscience
Rebecca S. James, Student – Sunlight Foundation in Washington DC
Mary Xia, Student – Yahoo in metro San Francisco
Anna Lysenko, Lab manager – clinical laboratory in metro DC area
Daniel Hwang, Research technician – Graduate student at University of Queensland
Antti Knaapila, Postdoctoral researcher – Postdoctoral Researcher at University of Turku
Amin Khoshnevisan, Research technician – Western University of Health Sciences, Dental School
Fujiko Duke, Lab manager Broad Institute – Matthew Meyerson lab
Amanda McDaniel, Research technician – BioElectroMed
Kirsten Mascioli, Research technician – Technical Specialist III at The Children’s Hospital of Philadelphia
Ke Lu, Research technician – Brigham and Women’s Hospital
Zhenyu Chen, Research technician – location unknown, Zhenyu please get in touch!
Rameen Starling-Roney, Student – Howard University College of Medicine, MD
Murtaza Shakir, Student – Aga Khan Medical School
Macrina Cooper-White, High school student – Yale University
Abigal Bosk, High school student – Wheaton College
Minna Bak, High school student – University of Pennsylvania
Sarah Obenrader, High school student – Davidson College
Brian Gantick, Research technician – Web designer
Mauricio Avigdor, Research technician – Novartis Institutes for BioMedical Research
Laurie Pippett, Research technician – Senior Administrative Assistant at Kelly Services

Twinsburg Alumni

Class of 2014

Seth Brockman
Fujiko Duke
Emily Evans
Brad Fesi
Rebecca James
Daniel Lee
Deborah Lee
Anna Lysenko
Alex Mangroo
Corrine Mansfield
Michael Marquis
Kevin Redding
Molly Stein
Ana Ulloa

Class of 2013

Seth Brockman
Fujiko Duke
Brad Fesi
Rebecca James
Daniel Lee
Deborah Lee
Anna Lysenko
Alex Mangroo
Corrine Mansfield
Michael Marquis
Kevin Redding

Class of 2012

Tiffany Weiss Aleman
Seth Brockman
Fujiko Duke
Brad Fesi
Daniel Hwang
Anna Lysenko
Alex Mangroo
Kevin Redding

Class of 2011

Seth Brockman
Danielle Crawford
Fujiko Duke
Daniel Hwang
Matt Kirkey
Anna Lysenko
Kevin Redding

Class of 2010

Laura Alarcon
Calvin Alarcon
Fujiko Duke
Brian R. Gantick
Matt Kirkey
Antti Knaapila
Amin Koshnevisan
Michelle Murphy
Tom Uleau

Class of 2009

Laura Alarcon
Fujiko Duke
Brian Gantick
Ryan McDermott