Contact Information

(267) 519-4823
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Karen Yee


Senior Research Associate, Monell Chemical Senses Center

Laboratory of

Dr. Robert Margolskee


Ph.D., Physiology; Virginia Commonwealth University

Research Summary

My research interest is in taste mechanisms, utilizing various methods (i.e., immunohistochemistry) to identify novel pathways in mammalian and human taste cells. Findings will provide additional knowledge about which components help modify taste sensitivity and function and their roles in gustatory function, appetite, satiety, diabetes and obesity. Another research interest is in the plasticity of mammalian olfactory system.


taste, cellular mechanisms, histology, olfactory

Recent Publications

Sukumaran, S. K.; Yee, K. K.; Iwata, S.; Kotha, R.; Quezada-Calvillo, R.; Nichols, B. L. et al. (2016) Taste cell-expressed alpha-glucosidase enzymes contribute to gustatory responses to disaccharides. Proceedings of the National Academy of Sciences USA, 113, 6035-6040.

Yee, K. K.; Craven, B. A.; Wysocki, C. J.; Van, V. B. (2016) Comparative Morphology and Histology of the Nasal Fossa in Four Mammals: Gray Squirrel, Bobcat, Coyote, and White-Tailed Deer. Anatomical Records, 299, 840-852.

Pang, B.; Yee, K. K.; Lischka, F. W.; Rawson, N. E.; Haskins, M. E.; Wysocki, C. J. et al. (2016) The influence of nasal airflow on respiratory and olfactory epithelial distribution in felids. Journal of Experimental Biology, 219, 1866-1874.

Kokrashvill, Z.; Yee, K.K.; Ilegems, E.; Iwatsuki, K.; Li, Y.; Mosinger, B.; Margolskee, R.F. (2014) Endocrine taste cells. British Journal of Nutrition, 2, 1-7.

Yee, K.K.; Sukumaran, S.K.; Kotha, R.; Gilbertson, T.A.; Margolskee, R.F. (2011) Glucose transporters and ATP-gated K+ (KATP) metabolic sensors are present in type 1 taste receptor 3 (T1r3)-expressing taste cells. Proceedings of the National Academy of Sciences USA, 108, 5421-1536.