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Monell Mouse Taste
Phenotyping Project


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Michael Tordoff

Affiliations

Member, Monell Chemical Senses Center

Education

Ph.D., Physiological Psychology; University of California, Los Angeles

Research Summary

My research interests are broadly focused on taste and nutrition. One area involves topics related to mineral appetite, including calcium taste and appetite, the physiology of salt intake, appetite specificity, and how the postingestive consequences of minerals influence taste preferences. Another area involves the genetics of taste perception, including the preferences for alcohol, sweetness, saltiness and calcium. A third area involves characterizing the environmental contribution to individual differences, particularly the influences of early environment, husbandry procedures, and food choice on taste preferences and dietary obesity.

Detailed description of research program

Keywords

specific appetite, calcium, taste genetics, ingestive behavior, obesity

Recent Publications

Saitou, K.; Lees, J.N.; Tordoff, M.G. (2014) Taste hedonics influence the disposition of fat by modulating gastric emptying in rats. PLoS ONE, 9, e90717.

Voznesenskaya, A.; Tordoff, M.G. (2013) Influence of cross-fostering on preference for calcium chloride in C57BL/6J and PWK/PhJ mice. Physiology & Behavior, 122, 159-162.

Tordoff, M.G.; Ellis, H.T. (2013) Taste dysfunction in BTBR mice due to a mutation of Itpr3, the inositol triphosphate receptor 3 gene. Physiological Genomics, 45, 834-855.

Voznesenskaya, A.; Tordoff, M.G.(2013) Influence of estrous and circadian cycles on calcium intake of the rat. Physiology & Behavior, 112-113, 56-60.

Taruno, A.; Vingtdeux, V.; Ohmoto, M.; Ma, Z.; Dvoryanchikov, G.; Li, A.; Adrien, L.; Zhao, H.; Leung, S.; Abernathy, M.; Koppel, J.; Davies, P.; Civan, M.M.; Chaudhari, N.; Matsumoto, I.; Hellekant, G.; Tordoff, M.G.; Marambaud, P.; Foskett, J.K. (2013) CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes. Nature, 495, 223-226.

Ellis, H.T.; Tordoff, M.G..; Parker, M.R. (2013) Itpr3 is responsible for the mouse tufted (tf) locus. Journal of Heredity, 104, 295-297.

Tordoff, M.G.; Aleman, T.R.; Murphy, M.C. (2012) No effects of monosodium glutamate consumption on the body weight or composition of adult rats and mice. Physiology & Behavior, 107, 338-345

Tordoff, M.G.; Alarcón, L.K.; Valmeki, S.; Jiang, P. (2012) T1R3: A human calcium taste receptor. Scientific Reports, 2, 496.

Tordoff, M.G.; Jaji, S.A.; Marks, J.M.; Ellis, H.T. (2012) Macronutrient choice of BTBR.NZW mice congenic for a 21-gene region of chromosome 17. Physiology & Behavior, 106, 556-561.

Cherukuri, C.M.; McCaughey, S.A.; Tordoff, M.G. (2011) Comparison of differences between PWD/PhJ and C57BL/6J mice in calcium solution preferences and chorda tympani nerve responses. Physiology & Behavior, 102, 496-502.

Tordoff, M.G. (2010) Taste solution consumption by FHH-Chr nBN consomic rats. Chemical Senses, 35, 473-489.

Lab Staff

Postdoctoral fellows
Anna Voznesenskaya
 
Technicians
Hillary Ellis
Tiffany Weiss