Contact Information

(267) 519-4915
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Danielle Reed

Affiliations

Associate Director, Monell Chemical Senses Center
Member, Monell Chemical Senses Center

Education

Ph.D., Psychology; Yale University

Research Summary

We do studies to understand the exact relationship between genotype and phenotype in both animal models and in human subjects including twins. Phenotypes of interest include taste perception, food preferences and obesity.

Keywords

sweet, genetics, taste, smell, obesity, genomics, genetic mapping

Recent Publications

Reed DR, Mainland JD, Arayata CJ. Sensory nutrition: The role of taste in the reviews of commercial food products. Physiol Behav. 2019 Jun 12;209:112579. doi: 10.1016/j.physbeh.2019.112579. [Epub ahead of print] PubMed PMID: 31199938.

Hwang LD, Lin C, Gharahkhani P, Cuellar-Partida G, Ong JS, An J, Gordon SD, Zhu G, MacGregor S, Lawlor DA, Breslin PAS, Wright MJ, Martin NG, Reed DR. New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances. Am J Clin Nutr. 2019 Jun 1;109(6):1724-1737. doi: 10.1093/ajcn/nqz043. PubMed PMID: 31005972; PubMed Central PMCID: PMC6537940.

Douglas JE, Lin C, Mansfield CJ, Arayata CJ, Cowart BJ, Spielman AI, Adappa ND, Palmer JN, Cohen NA, Reed DR. Tissue-Dependent Expression of Bitter Receptor TAS2R38 mRNA. Chem Senses. 2019 Jan 1;44(1):33-40. doi: 10.1093/chemse/bjy066. PubMed PMID: 30351347; PubMed Central PMCID: PMC6295798.

Shaw L, Mansfield C, Colquitt L, Lin C, Ferreira J, Emmetsberger J, Reed DR. Personalized expression of bitter ‘taste’ receptors in human skin. PLoS One. 2018 Oct 17;13(10):e0205322. doi: 10.1371/journal.pone.0205322. eCollection 2018. PubMed PMID: 30332676; PubMed Central PMCID: PMC6192714.

Hwang LD, Gharahkhani P, Breslin PAS, Gordon SD, Zhu G, Martin NG, Reed DR, Wright MJ. Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste. BMC Genomics. 2018 Sep 17;19(1):678. doi: 10.1186/s12864-018-5058-2. PubMed PMID: 30223776; PubMed Central PMCID: PMC6142396.

Douglas JE, Mansfield CJ, Arayata CJ, Cowart BJ, Colquitt LR, Maina IW, Blasetti MT, Cohen NA, Reed DR. Taste Exam: A Brief and Validated Test. J Vis Exp. 2018 Aug 17;(138). doi: 10.3791/56705. PubMed PMID: 30176005; PubMed Central PMCID: PMC6128106.

Lin C, Fesi BD, Marquis M, Bosak NP, Lysenko A, Koshnevisan MA, Duke FF, Theodorides ML, Nelson TM, McDaniel AH, Avigdor M, Arayata CJ, Shaw L, Bachmanov AA, Reed DR. Burly1 is a mouse QTL for lean body mass that maps to a 0.8-Mb region of chromosome 2. Mamm Genome. 2018 Jun;29(5-6):325-343. doi: 10.1007/s00335-018-9746-7. Epub 2018 May 8. PubMed PMID: 29737391.

Lin C, Fesi BD, Marquis M, Bosak NP, Lysenko A, Koshnevisan MA, Duke FF, Theodorides ML, Nelson TM, McDaniel AH, Avigdor M, Arayata CJ, Shaw L, Bachmanov AA, Reed DR. Adiposity QTL Adip20 decomposes into at least four loci when dissected using congenic strains. PLoS One. 2017 Dec 1;12(12):e0188972. doi: 10.1371/journal.pone.0188972. eCollection 2017. PubMed PMID: 29194435; PubMed Central PMCID: PMC5711020.

Lab Staff

Cailu Lin, Ph.D., Research Associate
Lauren Colquitt, B.S., Lab Manager
​Vicente Ramirez, a Ph.D. student visiting from University of California at Merced ​
Amber Suk, University of Pennsylvania undergraduate
​Desmond Johnson, ​University of Pennsylvania undergraduate​
​Aurora Hannikainen, Penn Charter high school student​
​With Noam Cohen:​
​Alyssa Civantos, University of Pennsylvania (medical student​)
​Monique Arnold, ​University of Pennsylvania (medical student​)
Poonia Seerat, M.D., University of Pennsylvania​ (medical ​resident)

Past Reed Lab Members

Postdoctoral fellows:​
Alissa Nolden,​ Ph.D.,​ Assistant Professor, University of Massachusetts at Amherst
​Paule Joseph, ​Ph.D., MS, FNP-BC, RN, CTN-B, Clinical Research Scholar, National Institute of Health
Sarah V. Lipchock​ Ph.D., Science Teacher at the ​Guston School
​Antti Knaapila, Ph.D., University Lecturer, University of Helsinki

​Sabbaticals​:
Juyun Lim Ph.D., Associate Professor, Oregon State University
​Raewyn Turner, ​Visual artist, Aukland New Zealand
Stephanie Lucianovic, Author “Suffering Succotash”

Technical staff:
Michael Marquis, Ph.C., Harvard University
Charles J. Arayata, Data Visualization and Reporting Analyst, Bayada Home Health Care
Daniel Hwang, Ph.D., Postdoctoral Fellow, University of Queensland
Amin Khoshnevisan, DMD, Oral & Maxillofacial Surgery
Fujiko Duke, B.S., Manager at Gritstone Oncology
Corrine Mansfield, B.S., M.S., Science teacher, Syracuse NY
Wendy Yu, B.S., Data Scientist, Quality Predictive Analytics Manager at Pfizer
Anna Lysenko, B.S., Embryologist, Shady Grove Fertility
Brian Gantick, Lead Developer at P’unk Avenue, LLC
Mauricio Avigdor, Drug Discovery​, ​In-vivo Pharmacology​, ​Preclinical Safety
Natalia Bosak, Ph.D., Monell Chemical Senses Center
Brad Fesi B.S., Research Technician, Temple University
Amanda McDaniel, B.S., Lead Research Biologist at Pulse Biosciences, Inc.
Kirsten Mascioli, Technical Specialist III at The Children’s Hospital of Philadelphia
Deborah Lee, B.S., O.D., Medical Resident
Ke Lu, Senior Technologist at Charles River Laboratories
Gabriel Galson, ​Masters in ​Library​ Science,​ Bibliographic Assistant II, Temple University
Amanda McKnight​, Archivist, Barnes Foundation​
Zhenyu Chen

​Medical students:
Jennifer Douglas, M.D., Penn Otolaryngology resident​
Ivy Maina, M.D., Penn Otolaryngology resident​
Rameen S. Starling-Roney, M.D., Anatomic pathology, Lehigh Valley Health Network
Murtaza Shakir​, M.D., FACS​, Southwest Surgical Associates

​Undergraduates​:
Lauren Shaw​, M.S., ​University of Pennsylvania​ (​now a graduate student​ at Penn)​
Durpri Lin, ​M.S., ​University of Pennsylvania
Mary Xia, B.S., University of Pennsylvania, Software Engineer
Rebecca S. James, B.S., University of Pennsylvania, Product Manager at Pivotal Labs
Kellen Wartnow B.A., University of Pennsylvania, Strategic Issues Analyst | U.S. Government Accountability Office
Emily Evans​ B.S., ​Washington College​, Tax Accountant at Radial​
​Molly Stein B.S., University of Pennsylvania, Associate, Network Partnerships at Oscar Health
Yasmine Boukataya​, ​University of Pennsylvania
​Gladys Tea, University of Pennsylvania

Volunteers:​
Joseph Whip

​High school students:
David Li​, ​now at ​Case Western University ​in Nursing​
Macrina Cooper-White, PhD Student in Social Neuroscience at UCLA
Abigal Bosk, Research Assistance at National Institutes of Health​
Minna Bak, Senior Manager at Helio Health Group
Sarah Obenrader, Davidson College
Steven Lui​, Cherry Hill High School
Raymond Lim​, Data Scientist at Facebook​
​Kirti Suri​, D.C. Licensed Attorney; J.D. from American University Washington College of Law​
​Arti Suri, Drexel University LeBow College of Business
Charlie Chen​, UI/UX Design​​, The New Office​
Steve Glotzhober​, Engineer at American Technology Solutions International Corp​

Twinsburg Alumni

Class of 2018

CJ Arayata
Nuala Bobowski
Lauren Colquitt
Fujiko Duke
Brad Fesi
Federica Genovese
Nicole Greenbaum
Desmond Johnson
Paule Johnson
Ivy Maina
Alex Mangroo
Corrine Mansfield
Michael Marquis
Lauren Shaw
Casey Trimmer

Class of 2017

CJ Arayata
Nuala Bobowski
Lauren Colquitt
Fujiko Duke
Hillary Ellis
Brad Fesi
Federica Genovese
Nicole Greenbaum
Alex Mangroo
Corrine Mansfield
Michael Marquis
Alissa Nolden
Lauren Shaw
Casey Trimmer

Class of 2016

CJ Arayata
Nuala Bobowski
Jennifer Douglas
Hillary Ellis
Brad Fesi
Marie Knoll
Alex Mangroo
Corrine Mansfield
Michael Marquis
Elliott McDowell
Lauren Shaw
Jake Saunders
Alyssa Treff
Casey Trimmer

Class of 2015

Kelsey Alderman
CJ Arayata
Nuala Bobowski
Laurel Doghramji
Jennifer Douglas
Hilary Ellis
Brad Fesi
Nicole Greenbaum
Rebecca James
John Lees
Alex Mangroo
Corrine Mansfield
Michael Marquis
Lauren Shaw
Casey Trimmer

Class of 2014

Seth Brockman
Fujiko Duke
Emily Evans
Brad Fesi
Rebecca James
Daniel Lee
Deborah Lee
Anna Lysenko
Alex Mangroo
Corrine Mansfield
Michael Marquis
Kevin Redding
Molly Stein
Ana Ulloa

Class of 2013

Seth Brockman
Fujiko Duke
Brad Fesi
Rebecca James
Daniel Lee
Deborah Lee
Anna Lysenko
Alex Mangroo
Corrine Mansfield
Michael Marquis
Kevin Redding

Class of 2012

Tiffany Weiss Aleman
Seth Brockman
Fujiko Duke
Brad Fesi
Daniel Hwang
Anna Lysenko
Alex Mangroo
Kevin Redding

Class of 2011

Seth Brockman
Danielle Crawford
Fujiko Duke
Daniel Hwang
Matt Kirkey
Anna Lysenko
Kevin Redding

Class of 2010

Laura Alarcon
Calvin Alarcon
Fujiko Duke
Brian R. Gantick
Matt Kirkey
Antti Knaapila
Amin Koshnevisan
Michelle Murphy
Tom Uleau

Class of 2009

Laura Alarcon
Fujiko Duke
Brian Gantick
Ryan McDermott