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(267) 519-4805
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Monell Mouse Taste
Phenotyping Project


Michael Tordoff


Member, Monell Chemical Senses Center


Ph.D., Physiological Psychology; University of California, Los Angeles

Research Summary

My research interests are broadly focused on taste and nutrition. One area involves topics related to mineral appetite, including calcium taste and appetite, the physiology of salt intake, appetite specificity, and how the postingestive consequences of minerals influence taste preferences. Another area involves the genetics of taste perception, including the preferences for alcohol, sweetness, saltiness and calcium. A third area involves characterizing the environmental contribution to individual differences, particularly the influences of early environment, husbandry procedures, and food choice on taste preferences and dietary obesity.

Detailed description of research program


specific appetite, calcium, taste genetics, ingestive behavior, obesity

Recent Publications

Baird, J.P.; Tordoff, M.G.; McCaughey, S.A. (In Press) Bursting by taste-responsive cells in the rodent brainstem. Journal of Neurophysiology.

Saitou, K.; Lees, J.N.; Tordoff, M.G. (2014) Taste hedonics influence the disposition of fat by modulating gastric emptying in rats. PLoS ONE, 9, e90717.

Tordoff, M.G.; Downing, A.; Voznesenskaya, A. (2014) Macronutrient selection by seven inbred mouse strains and three taste-related knockout strains. Physiology and Behavior, 35, 49-54.

Tordoff, M.G.; Ellis, H.T.; Aleman, T.R.; Downing, A.; Mrambaud, P.; et al. (2014) Salty taste deficits in CALHM1 knockout mice. Chemical Senses. (Electronic citation) doi:10.1093/chemse/bju020

Tordoff, M.; Jiang, P.; Valmeki, S.; Aleman, T.; McCaughey, S. (In Press) Heightened avidity for trisodium pyrophosphate in mice lacking Tas1r3. Chemical Senses.

Ellis, H.T.; Tordoff, M.G..; Parker, M.R. (2013) Itpr3 is responsible for the mouse tufted (tf) locus. Journal of Heredity, 104, 295-297.

Taruno, A.; Vingtdeux, V.; Ohmoto, M.; Ma, Z.; Dvoryanchikov, G.; Li, A.; Adrien, L.; Zhao, H.; Leung, S.; Abernathy, M.; Koppel, J.; Davies, P.; Civan, M.M.; Chaudhari, N.; Matsumoto, I.; Hellekant, G.; Tordoff, M.G.; Marambaud, P.; Foskett, J.K. (2013) CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes. Nature, 495, 223-226.

Tordoff, M.G.; Ellis, H.T. (2013) Taste dysfunction in BTBR mice due to a mutation of Itpr3, the inositol triphosphate receptor 3 gene. Physiological Genomics, 45, 834-855.

Voznesenskaya, A.; Tordoff, M.G.(2013) Influence of estrous and circadian cycles on calcium intake of the rat. Physiology & Behavior, 112-113, 56-60.

Voznesenskaya, A.; Tordoff, M.G. (2013) Influence of cross-fostering on preference for calcium chloride in C57BL/6J and PWK/PhJ mice. Physiology & Behavior, 122, 159-162.

Tordoff, M.G.; Alarcón, L.K.; Valmeki, S.; Jiang, P. (2012) T1R3: A human calcium taste receptor. Scientific Reports, 2, 496.

Tordoff, M.G.; Aleman, T.R.; Murphy, M.C. (2012) No effects of monosodium glutamate consumption on the body weight or composition of adult rats and mice. Physiology & Behavior, 107, 338-345

Tordoff, M.G.; Jaji, S.A.; Marks, J.M.; Ellis, H.T. (2012) Macronutrient choice of BTBR.NZW mice congenic for a 21-gene region of chromosome 17. Physiology & Behavior, 106, 556-561.

Cherukuri, C.M.; McCaughey, S.A.; Tordoff, M.G. (2011) Comparison of differences between PWD/PhJ and C57BL/6J mice in calcium solution preferences and chorda tympani nerve responses. Physiology & Behavior, 102, 496-502.

Tordoff, M.G. (2010) Taste solution consumption by FHH-Chr nBN consomic rats. Chemical Senses, 35, 473-489.

Lab Staff

Hillary Ellis
Tiffany Weiss